{"id":1138,"date":"2022-09-17T16:14:18","date_gmt":"2022-09-17T15:14:18","guid":{"rendered":"https:\/\/rdu.if.ua\/?p=1138"},"modified":"2022-09-17T16:18:45","modified_gmt":"2022-09-17T15:18:45","slug":"evaluation-of-biological-effects-of-graphene-oxide-using-drosophila","status":"publish","type":"post","link":"https:\/\/rdu.if.ua\/en\/evaluation-of-biological-effects-of-graphene-oxide-using-drosophila\/","title":{"rendered":"Evaluation of biological effects of graphene oxide using Drosophila"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_spacing=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text css=&#8221;.vc_custom_1663427501390{padding-bottom: 3% !important;}&#8221;]<span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1141 size-full\" src=\"https:\/\/rdu.if.ua\/wp-content\/uploads\/2022\/09\/photo_2022-09-17_18-11-11.jpg\" alt=\"\" width=\"378\" height=\"198\" srcset=\"https:\/\/rdu.if.ua\/wp-content\/uploads\/2022\/09\/photo_2022-09-17_18-11-11.jpg 378w, https:\/\/rdu.if.ua\/wp-content\/uploads\/2022\/09\/photo_2022-09-17_18-11-11-300x157.jpg 300w\" sizes=\"auto, (max-width: 378px) 100vw, 378px\" \/><br \/>\nGraphene and its derivatives have attracted great interest because of their intriguing physical and chemical properties. An increasing phase of commercial production causes the presence of graphene in the environment and might pose a great threat to a wide range of living organisms, including bacteria, viruses, plants, invertebrates and mammals, including humans. In the present study, the graphene oxide (GO) at low doses was evaluated for its biological effects on larvae and the imago of\u00a0<em>Drosophila melanogaster<\/em>. Oral administration of GO at concentrations of 0.02-1% has a beneficial effect on the developmental rate and hatching ability of larvae. Long-term administration of a low dose of GO extends\u00a0<em>Drosophila<\/em>\u00a0lifespan and significantly enhances resistance to environmental stresses. We also found that GO exposure led to a remarkable decrease in the level of hemolymph glucose, glycogen and triglycerides storage. These suggest about GO affects carbohydrate and lipid metabolism in adult\u00a0<em>Drosophila<\/em>. These findings might provide a useful reference to assess the biological effects of GO, which could play an important role in a variety of graphene-based biomedical applications.<br \/>\n<\/span>[\/vc_column_text][nectar_btn size=&#8221;large&#8221; open_new_tab=&#8221;true&#8221; button_style=&#8221;see-through&#8221; button_color_2=&#8221;Accent-Color&#8221; color_override=&#8221;#2954aa&#8221; icon_family=&#8221;default_arrow&#8221; text=&#8221;Read the full article&#8221; url=&#8221;https:\/\/scijournals.pnu.edu.ua\/index.php\/pcss\/article\/view\/5751&#8243;][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>Graphene  and  its  derivatives  have  attracted  great  interest  because  of  their  intriguing  physical  and chemical properties. An increasing phase of commercial production causes the presence of graphene in the environment and might pose a great threat to a widerange of living organisms, including bacteria, viruses, plants, invertebrates and mammals,  including  humans. <\/p>\n","protected":false},"author":1,"featured_media":1141,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[17],"tags":[],"class_list":{"0":"post-1138","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-researches-en"},"_links":{"self":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/comments?post=1138"}],"version-history":[{"count":2,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1138\/revisions"}],"predecessor-version":[{"id":1144,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1138\/revisions\/1144"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/media\/1141"}],"wp:attachment":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/media?parent=1138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/categories?post=1138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/tags?post=1138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}