{"id":1337,"date":"2024-02-03T20:28:16","date_gmt":"2024-02-03T20:28:16","guid":{"rendered":"https:\/\/rdu.if.ua\/?p=1337"},"modified":"2024-02-24T20:38:22","modified_gmt":"2024-02-24T20:38:22","slug":"high-fat-high-fructose-diet-and-alpha-ketoglutarate-affect-mouse-behavior-that-is-accompanied-by-changes-in-oxidative-stress-response-and-energy-metabolism-in-the-cerebral-cortex","status":"publish","type":"post","link":"https:\/\/rdu.if.ua\/en\/high-fat-high-fructose-diet-and-alpha-ketoglutarate-affect-mouse-behavior-that-is-accompanied-by-changes-in-oxidative-stress-response-and-energy-metabolism-in-the-cerebral-cortex\/","title":{"rendered":"High-fat high-fructose diet and alpha-ketoglutarate affect mouse behavior that is accompanied by changes in oxidative stress response and energy metabolism in the cerebral cortex"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_spacing=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text css=&#8221;.vc_custom_1708806713559{padding-bottom: 3% !important;}&#8221;]<span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1339 size-medium\" src=\"https:\/\/rdu.if.ua\/wp-content\/uploads\/2024\/02\/X03044165-225x300.jpg\" alt=\"\" width=\"225\" height=\"300\" srcset=\"https:\/\/rdu.if.ua\/wp-content\/uploads\/2024\/02\/X03044165-225x300.jpg 225w, https:\/\/rdu.if.ua\/wp-content\/uploads\/2024\/02\/X03044165.jpg 576w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><br \/>\nHigh caloric diets with high amounts of fats and sweeteners such as fructose may predispose organisms to neurodegenerative diseases.<br \/>\nThis study aimed to examine the effects of a high-fat high-fructose diet (HFFD) on the behavior of mice, energy metabolism, and markers of\u00a0<a class=\"topic-link\" title=\"Learn more about oxidative stress from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/oxidative-stress\">oxidative stress<\/a>\u00a0in murine cerebral cortex. Dietary \u03b1-ketoglutarate (AKG) was chosen as a treatment which could modulate the putative effects of HFFD.<br \/>\n<\/span>[\/vc_column_text][nectar_btn size=&#8221;large&#8221; open_new_tab=&#8221;true&#8221; button_style=&#8221;see-through&#8221; button_color_2=&#8221;Accent-Color&#8221; color_override=&#8221;#2954aa&#8221; icon_family=&#8221;default_arrow&#8221; text=&#8221;Read the full article&#8221; url=&#8221;https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0304416523002192?via%3Dihub&#8221;][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>High caloric diets with high amounts of fats and sweeteners such as fructose may predispose organisms to neurodegenerative diseases.<br \/>\nThis study aimed to examine the effects of a high-fat high-fructose diet (HFFD) on the behavior of mice, energy metabolism, and markers of oxidative stress in murine cerebral cortex.<\/p>\n","protected":false},"author":1,"featured_media":1341,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[17],"tags":[],"class_list":{"0":"post-1337","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-researches-en"},"_links":{"self":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/comments?post=1337"}],"version-history":[{"count":2,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1337\/revisions"}],"predecessor-version":[{"id":1345,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1337\/revisions\/1345"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/media\/1341"}],"wp:attachment":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/media?parent=1337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/categories?post=1337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/tags?post=1337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}