{"id":1382,"date":"2024-02-10T20:38:20","date_gmt":"2024-02-10T20:38:20","guid":{"rendered":"https:\/\/rdu.if.ua\/?p=1382"},"modified":"2024-03-04T20:44:27","modified_gmt":"2024-03-04T20:44:27","slug":"impact-of-caloric-restriction-on-oxidative-stress-and-key-glycolytic-enzymes","status":"publish","type":"post","link":"https:\/\/rdu.if.ua\/en\/impact-of-caloric-restriction-on-oxidative-stress-and-key-glycolytic-enzymes\/","title":{"rendered":"Impact of caloric restriction on oxidative stress and key glycolytic enzymes in the cerebral cortex, liver and kidney of old and middle-aged mice"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_spacing=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text css=&#8221;.vc_custom_1709585063528{padding-bottom: 3% !important;}&#8221;]<span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1386 size-medium\" src=\"https:\/\/rdu.if.ua\/wp-content\/uploads\/2024\/03\/X00283908-225x300.jpg\" alt=\"\" width=\"225\" height=\"300\" srcset=\"https:\/\/rdu.if.ua\/wp-content\/uploads\/2024\/03\/X00283908-225x300.jpg 225w, https:\/\/rdu.if.ua\/wp-content\/uploads\/2024\/03\/X00283908.jpg 576w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><br \/>\nCaloric restriction (CR) is proposed as a strategy to prevent age-related alterations like impaired glucose metabolism and intensification of oxidative stress. In this study, we examined effects of aging and CR on the activities of glycolytic enzymes and parameters of oxidative stress in the cerebral cortex, liver, and kidney of middle-aged (9 months old) and old (18 months old) C57BL6\/N mice. Control middle-aged and old mice were fed\u00a0<em>ad libitum<\/em>\u00a0(AL groups), whereas age-matched CR groups were subjected to CR (70% of individual\u00a0<em>ad libitum<\/em> food intake) for 6 and 12 months, respectively.<br \/>\n<\/span>[\/vc_column_text][nectar_btn size=&#8221;large&#8221; open_new_tab=&#8221;true&#8221; button_style=&#8221;see-through&#8221; button_color_2=&#8221;Accent-Color&#8221; color_override=&#8221;#2954aa&#8221; icon_family=&#8221;default_arrow&#8221; text=&#8221;Read the full article&#8221; url=&#8221;https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002839082400025X?via%3Dihub&#8221;][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>Caloric restriction (CR) is proposed as a strategy to prevent age-related alterations like impaired glucose metabolism and intensification of oxidative stress. In this study, we examined effects of aging and CR on the activities of glycolytic enzymes and parameters of oxidative stress in the cerebral cortex, liver, and kidney of middle-aged (9 months old) and old (18 months old) C57BL6\/N mice.<\/p>\n","protected":false},"author":1,"featured_media":1384,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[17],"tags":[],"class_list":{"0":"post-1382","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-researches-en"},"_links":{"self":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/comments?post=1382"}],"version-history":[{"count":3,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1382\/revisions"}],"predecessor-version":[{"id":1392,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/posts\/1382\/revisions\/1392"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/media\/1384"}],"wp:attachment":[{"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/media?parent=1382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/categories?post=1382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rdu.if.ua\/en\/wp-json\/wp\/v2\/tags?post=1382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}